ASUS ExpertCenter D5 Mini Tower (D501MER)
ASUS ExpertCenter D5 Mini Tower (D501MER)
Enterprise-grade security and scalable manageability


  • Windows 11 Pro - ASUS recommends Windows 11 Pro for business
  • Up to Intel® Core™ i7 14th gen Processor
  • Up to NVIDIA® GeForce® RTX 4060 graphics
  • 15L compact and tool-free chassis for maximum expandability
  • Durability-tested to MIL-STD 810H military-grade standard and ASUS in-house testing
  • Extensive I/O ports to support all your connectivity needs

Request for Volume Purchase
A right 45-degree angle view of ASUS ExpertCenter D5 Mini Tower D500MER

Outstanding Value for business at any sizes

Engineered specifically for the specific demands of small businesses, the ASUS ExpertCenter D5 Mini Tower is a desktop with AI-driven Microsoft Copilot that boasts powerful, trustworthy, and expandable performance. Its modern, compact, and flexible design caters to diverse workspaces and usage scenarioses. Take advantage of our simplified small-business support services to experience reduced downtime and a more economical total cost of ownership.
A reliability icon.
Secure manageability
ExpertCenter D5 Mini Tower prioritizes security through TPM 2.01, providing advanced protection with two options: Firmware TPM, a software-based solution running on the CPU, and Discrete TPM, a dedicated chip offering an additional layer of defense against sophisticated threats.
An expandability icon.
Efficient expandability
The perfect balance of performance and size with remarkable expandability that provides space for essential hardware to support diverse productivity needs.
A tool-free icon.
Tool-free chassis
The redesigned tool-free chassis makes it easier to remove components by hand, simplifying routine servicing and making future upgrades a breeze.
A reliability icon.
Ultimate reliability
Built with industry-leading ASUS motherboards and tested to stringent ASUS and MIL-STD 810H US military standards2, minimizing risk of damage and maximizing longevity.

Exceptional performance, whatever the task

To make light work of all your business tasks, ExpertCenter D5 Mini Tower is powered by the latest Intel® Core™ 14th gen processors with up to 64 GB DDR5 RAM. An NVIDIA® discrete GPU is an option for those requiring advanced graphics performance for demanding visual tasks.
Windows 11 Pro
 
14th Gen
Intel® CPU
Up to
64 GB
DDR5 RAM
Up to
2 TB + 2 TB
HDD + SSD3

Microsoft Copilot

AI-powered Microsoft Copilot4 in Windows with commercial data protection is your Al assistant at work. Supercharge your productivity and achieve more with less time and effort using Copilot AI. Experience your everyday Al companion now with the dedicated Copilot key. Just one click for endless exploration.

Maximize your workspace

The ExpertCenter D5 Mini Tower desktop with AI-enhanced Microsoft Copilot is 42%5 smaller than a traditional tower PC, helping to maximize your office workspace. And its sleek and elegant design gives your business a truly professional look — ready to work in style.
An ExpertCenter D5 Mini Tower is placed on the table with a bigger translucent, virtual desktop outline on top, and a pen holder on the right.

AI noise-canceling audio technology for business

To level up professional conferencing, ExpertCenter D5 Mini Tower has two-way AI noise-canceling technology7 that employs sophisticated machine-learning techniques. The technology includes both an upstream function to filter noise around the speaker, and a downstream function to eliminate noise from the person at the other end of the conversation. Try the demo to experience the amazing difference that ASUS two-way AI noise-canceling technology can make.
Turn on your device’s audio and press play to experience AI noise-canceling technology.
Committed to creating a sustainable future, ASUS ensures all its products are compliant with environmental requirements at all stages of their product life cycles. The ExpertCenter D5 Mini Tower is registered as EPEAT Gold8, and is also ENERGY STAR® 8.0-certified to reduce long-term costs with its energy-efficient design.
Expert-series PCs are solidly-built and tested to the most demanding industry requirements, including MIL-STD 810H US military standards and stringent ASUS in-house testing. The inevitable minor shocks and everyday workplace accidents won’t jeopardize your precious data2.

Ready for the business world

A full array of I/O ports is ready to connect ExpertCenter D5 Mini Tower to a wide range of business peripherals. It has four front-mounted USB ports for quick and easy access and flexible serial and parallel ports on chassis leave more PCI Express® slots available for additional upgrades. A smart-card reader and an optional SD card reader for easy transactions, data transfer, or other business-related tasks.
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  1. Actual product appearances may vary, and the images displayed are for illustrative purposes only; please refer to product descriptions for accurate information.
  1. Trusted Platform Module (TPM) is optional.
  2. The testing regime includes the requirements of both military-grade standards and ASUS quality tests and varies depending on device. MIL-STD-810H testing is conducted on selected ASUS products only. Note that the MIL-STD-810H testing helps to ensure the quality of ASUS products but does not indicate a particular fitness for military use. The test is performed under laboratory conditions. Any damage caused by attempts to replicate these test conditions would be considered accidental and would not be covered by the standard ASUS warranty. Additional coverage is available with ASUS Premium Care.
  3. Please note that ExpertCenter D5 Mini Tower includes up to 2 x 1 TB M.2 SSD, and up to 1 x 2 TB 3.5” HDD, for total storage capacity of up to 4 TB.
  4. a) Screen simulated, subject to change. Feature availability and rollout timing varies by market and device.
    b) Copilot in Windows (in preview) is rolling out gradually within the latest update to Windows 11 in select global markets. Timing of availability varies by device and market. Learn more: http://www.microsoft.com/en-us/windows/copilot-ai-features?r=1#faq
    c) Copilot with commercial data protection requires Microsoft 365 E3, E5, Business Standard, Business Premium or A3 or A5 for faculty, or accessed using Microsoft Entra ID.
  5. Based on ASUS measurements and internal testing. Unless otherwise stated, all performance claims are based on theoretical performance. Actual figures may vary in real-world situations.
  6. ASUS Service Package options include: 24x7 support; MyASUS app; Three-year international warranty; Pick up & return service; Onsite service; Next business day onsite response; Accidental damage protection; Defective HDD retention. Service and warranty coverage may vary depending on country and territory. Service may not be available in all markets. We recommend that you check with your local retailers to confirm the options available.
  7. AI noise-canceling audio technology only applies when connected to external mics.
  8. D501MERS refers to the SKUs of D501MER with Energy Star and EPEAT certifications.
  9. ASUS Endpoint Management Service (AEMS) and ASUS Pre-Deployment Service (APDS) are optional, and their availability varies according to country. Please check with your local ASUS retailer for details.
  10. ASUS secured the #1 spot for motherboard market share as of 2017, with DigiTimes reporting that the Taiwanese PC component giant owns 45% of the motherboard market.
  • Products certified by the Federal Communications Commission and Industry Canada will be distributed in the United States and Canada. Please visit the ASUS USA and ASUS Canada websites for information about locally available products.
  • All specifications are subject to change without notice. Please check with your supplier for exact offers. Products may not be available in all markets.
  • Specifications and features vary by model, and all images are illustrative. Please refer to specification pages for full details.
  • PCB color and bundled software versions are subject to change without notice.
  • Brand and product names mentioned are trademarks of their respective companies.
  • The terms HDMI and HDMI High-Definition Multimedia Interface, HDMI trade dress and the HDMI Logos are trademarks or registered trademarks of HDMI Licensing Administrator, Inc. in the United States and other countries.

¹Device comes with Windows 10 and a free Windows 11 upgrade or may be preloaded with Windows 11. Upgrade timing may vary by device. Features and app availability may vary by region. Certain features require specific hardware (see Windows 11 Specifications: http://www.microsoft.com/windows/windows-11-specifications).

Unless otherwise stated, all performance claims are based on theoretical performance. Actual figures may vary in real-world situations.

The actual transfer speed of USB 3.0, 3.1, 3.2, and/or Type-C will vary depending on many factors including the processing speed of the host device, file attributes and other factors related to system configuration and your operating environment.

* The testing regimen includes the requirements of both military-grade standards and ASUS quality tests, and varies depending on device. MIL-STD-810 testing is conducted on selected ASUS products only. These tests do not demonstrate fitness for military use, or adherence to US Department of Defense (DoD) contract requirements. Similarly, the test results should not be considered an indication or guarantee of future performance under the specified test conditions. Damage occurring under these test conditions – or any attempt to replicate them – would be considered accidental, and would not be covered by the standard ASUS warranty. Additional coverage is available with ASUS Premium Care.

  • Price may not include extra fee, including tax、shipping、handling、recycling fee.
  • For pricing information, ASUS is only entitled to set a recommendation resale price. All resellers are free to set their own price as they wish.